The problem
Neurosurgeons still drill skulls to measure brain pressure. Every non-invasive approach — transcranial Doppler, optic nerve sheath, tympanometry — fails calibration. The 95% limits of agreement remain ±7–15 mmHg, clinically unacceptable.
Vitacore approach
Adaptive filtering and multipath cancellation techniques from telecommunications applied to ICP estimation. The skull and brain modelled as an inhomogeneous transmission medium with a patient-specific transfer function derived from multimodal non-invasive signals.
Output
Target venue: Critical Care Medicine · Journal of Neural Engineering · IEEE TBME.
Theoretical framework paper: 8–10 weeks.